Search on: 2-HYDROXY-5-NITROBENZYL BROMIDE 
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Descriptor English:   2-Hydroxy-5-nitrobenzyl Bromide 
Descriptor Spanish:   2-Hidroxi-5-nitrobencil Bromuro 
Descriptor Portuguese:   2-Hidroxi-5-nitrobenzil Brometo 
Synonyms English:   Koshland's Reagent I  
Tree Number:   D02.455.426.559.389.140.400
D02.455.426.559.389.657.566.400
D02.640.743.400
Definition English:   A chemical reagent that reacts with and modifies chemically the tryptophan portion of protein molecules. Used for 'active site' enzyme studies and other protein studies. Sometimes referred to as Koshland's reagent. 
Indexing Annotation English:   D25-26 qualif
Pharmacological Action:   Indicators and Reagents
 
History Note English:   91(75); was see under NITROPHENOLS 1975-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AA analogs & derivatives AN analysis
CS chemical synthesis CH chemistry
CL classification CT contraindications
EC economics HI history
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
Record Number:   7076 
Unique Identifier:   D015077 

Occurrence in VHL:
 

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